منابع مشابه
A RAVE about Opioid Withdrawal
Control of trafficking of g protein-linked receptors is thought to be an important regulatory mechanism for receptor signaling. Finn and Whistler test the hypothesis that agonist-induced trafficking of opioid receptors regulates the development of tolerance and dependence. The results show that measures of tolerance and withdrawal to morphine are decreased under conditions where receptors are t...
متن کاملOpioid tolerance or opioid withdrawal?
To the Editor: We thank Kim et al. for their recent work examining the effect of intraoperative remifentanil on postoperative analgesia in children.1 Certainly, the pharmacokinetic profile of this potent opioid is attractive in modern anesthetic practice, and a thorough understanding of the principles behind tolerance, hyperalgesia, and withdrawal of remifentanil are critical for its safe admin...
متن کاملWhat's All the RAVE about Receptor Internalization?
physiologic role of the perineurial barrier. dhh null mice transduction and cell surface receptor expression. Recent studies have suggested that, in some cases, GPCR-may provide a useful model for investigations of the biological function of this barrier, both in physiologic mediated endocytosis may also be important for mediating other biological actions of receptor occupancy. and pathologic s...
متن کاملA Review on Hematological Factors in Opioid-Dependent People (Opium and Heroin) after the Withdrawal Period
Abstract Background: Long-term use of opioids has acute effects on homeostasis of the body. Discovering the impacts of opioids on hematological parameters of narcotics withdrawal and dependents blood may be helpful in recognizing the homeostasis condition of their body for the useful treatment. Methods: In this study a cross-sectional method was applied. The abusers of opium and her...
متن کامل154 - Ethanol and Opioid Intoxication and Withdrawal
their lifetimes. Mild to moderate consumption (up to one drink/day for women and two drinks/day for men) has been shown to have beneficial cardiovascular effects, including a decreased risk of myocardial infarction and stroke, as well as overall decreased mortality (Box 154.1). Despite these possibly beneficial effects of alcohol, it has been found to be a top 10 cause of preventable deaths amo...
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ژورنال
عنوان ژورنال: Neuron
سال: 2001
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(01)00530-x